San Francisco 49ers tight end George Kittle again lost his annual Iowa vs. Iowa State bet to teammate Brock Purdy.

But the 25-year-old Purdy, who signed a mammoth $265 million extension with the 49ers over the offseason, raises the ceiling of the entire offense. A return after just two games missed would also be a major positive given how troubling the initial information was on Purdy’s injury.

Facing perennial issues keeping key players healthy, the 49ers have two injured quarterbacks entering Week 4. Mac Jones joins Brock

Quarterback Mac Jones, already serving in relief duty for the injured Brock Purdy, told reporters after Sunday's 16-15 win over the Arizona Cardinals that he reaggravated the same PCL sprain that hampered him during training camp.