OTTAWA—Canada’s Finance Minister Chrystia Freeland quit the Liberal government cabinet Monday, a surprise departure that casts further doubts about how long Prime Minister Justin Trudeau can hold on to his job given the government’s deep unpopularity.

Canada's Finance Minister Chrystia Freeland quit on Monday after clashing with Prime Minister Justin Trudeau on issues including how to handle possible U.S. tariffs, dealing a huge blow to an already unpopular government.

The departure of Chrystia Freeland, who had been helping lead Canada’s response to the incoming Trump administration, threatens Prime Minister Justin Trudeau’s hold on power.