Dominick Puni is believed to have injured his posterior cruciate ligament and could miss a few weeks, coach Kyle Shanahan said after Saturday's preseason game.

Multiple preseason injuries created serious questions about San Francisco’s offensive line stability and backfield depth heading into Week 1.

The San Francisco 49ers lost starting right guard Dominic Puni and two other offensive players in the first half of their 22-19 preseason win over the Las Vegas Raiders.

The Niners’ first team (whatever that might be these days) looked good, while the depth pieces struggled against the Raiders.

The San Francisco 49ers will face the Las Vegas Raiders in week 2 of the NFL preseason on Saturday at Allegiant Stadium.

And the 49ers are thankful every single day that they took a chance on the underutilized Iowa tight end.

Former NFL player Kirk Morrison has told Brock Purdy that he needs to do one thing this season for the San Francisco 49ers.

The 2024 campaign was a lost season for the San Francisco 49ers. Coming off a narrow, heartbreaking loss in Super Bowl LVIII, they were hoping to finally make good on their prolonged "Quest for Six," only to suffer a prolonged string of key injuries. As a result of those injuries, they went 6-11 and missed the playoffs.