Predictions, picks and odds for NFL Week 8 game
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San Francisco 49ers, Brock Purdy and Houston Texans
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Texans Wire on MSN
ESPN calls Texans 'NFL worst offseason' among all teams after 2-4 start
Change was expected to come to the Texans after back-to-back postseason appearances, but six games into the season and it looks like regression.
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49ers at Texans prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats
Despite being one of the most banged-up teams in the NFL, San Francisco sits tied atop the NFC West with the Seahawks and the Rams. A big reason is the play of Jones under center. The veteran has resurrected his career in leading San Francisco forward despite injuries to a laundry list of players including Brock Purdy, Brandon Aiyuk, and Nick Bosa.
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Houston’s Ryans faces former boss San Francisco’s Shanahan for 1st time when Texans host Niners
Houston coach DeMeco Ryans will face his former boss San Francisco coach Kyle Shanahan for the first time Sunday when the Texans host the 49ers.
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The Texans' defense is No. 1 in the NFL. Inside Houston's mindset. 'Have you ever seen lions hunt?'
The Houston Texans have the No. 1 defense in the NFL. Inside their mindset and what it's like to face a team that can beat you in many ways.
Texans Wire on MSN
All 32 NFL teams (including the Texans) ranked by FPI ratings
Here's where the Texans stack up in FPI ratings entering their Week 8 showdown against the San Francisco 49ers
Colin Cowherd picks his best predictions for Week 8 of the 2025/26 NFL season, including the Baltimore Ravens over the Chicago Bears, the New England Patriots over the Cleveland Browns, and the Houston Texans beating the San Francisco 49ers.
Oct 19, 2025; Santa Clara, California, USA; San Francisco 49ers running back Christian McCaffrey (23) celebrates after a touchdown during the second quarter against the Atlanta Falcons at Levi's Stadium. Mandatory Credit: Kyle Terada-Imagn Images / Darren Yamashita-Imagn Images
C.J. Stroud and the Houston Texans offense had few answers for the Seattle Seahawks defense on Monday night. Houston managed just 254 total yards and scored just one offensive touchdown in the 27-19 defeat. A bulk of the yards came in the fourth quarter when the Texans attempted to claw back into the game.