In the new study, the team used the model to demonstrate that as Alzheimer's pathology accumulates in the brain, specific types of immune cells called CT8+ T Cells surge into the brain and amplify the ...

Research and drug discovery are undergoing a transformation, driven by the rise of 3D cell culture models that better replicate human biology. Unlike traditional 2D cultures and animal models, which ...

Neuronal death is the indisputable endgame of Alzheimer’s disease, but what does the killing, and how? To try to solve the mystery, researchers have staged increasingly complex crime scenes in ...

3D-printed lungs made with living cells could help to improve lung disease prevention and treatment—and potentially one day offer a lab-grown option for use in organ transplants. University of ...

As organoids, organ-on-chip systems, and other non-animal models (NAMs) move from specialized innovation into mainstream drug discovery, laboratories are confronting a new reality. Biological models ...

Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...

Researchers developed a new 3D model of Alzheimer’s Disease that allows them to study the role of immune cells in the disease They found that infiltration of immune cells significantly increases in ...