The San Francisco 49ers (9-4) will face the Tennessee Titans (2-11) in Week 15 at Levi’s Stadium, with all eyes on star running back Christian McCaffrey. McCaffrey was a late addition to the injury report on Saturday with a back issue, earning a questionable designation.

As the 49ers return from their bye and host the Tennessee Titans, the fantasy landscape for this matchup looks very different from what it would have earlier in the season. Tennessee, meanwhile, is still searching for rhythm with a rookie quarterback and a reshaped skill-position group that no longer includes Derrick Henry or DeAndre Hopkins.

RB Christian McCaffrey is expected to play vs. the Titans despite a questionable tag, with multiple NFL insiders signaling good news.

The San Francisco 49ers are playing in the toughest division in all of the NFL

San Francisco 49ers DE Sam Okuayinonu had a great list featuring mostly his teammates for the NFL Top 100.

So if the Niners let him play out his contract, shake his hand, and watch him sign a solid $20-to-$30 (maybe $40) million-dollar deal elsewhere in free agency come the end of the 2026 season, the league office will essentially FedEx a third-round pick (fourth at worst) to Santa Clara. That’s money in the bank. That’s a free lottery ticket.

Did you draft the Vikings as your starting fantasy football defense? Does your regular starter have a bad matchup and you’re looking for help at the position th

His lack of productivity since his return has been head-scratching, but offensive coordinator Klay Kubiak on Thursday in a press conference insisted there isn't an underlying issue. Instead, he pointed to specific examples of missed opportunities in each game.