While many changes have been observed in the brains of Alzheimer's disease patients, amyloid plaques are considered a hallmark of the disease. Though beta-amyloid has not been shown conclusively to be ...

An impressive new study is presenting robust evidence showing the toxic proteins thought to be the cause of Alzheimer’s disease may be produced in the liver and travel through the blood before landing ...

Amyloid protein made in the liver can cause neurodegeneration in the brain, according to a new study. Since the protein is thought to be a key contributor to development of Alzheimer's disease (AD), ...

Selkoe is co-director of the Ann Romney Center for Neurologic Diseases, Department of Neurology, Mass General Brigham, and Vincent and Stella Coates professor of neurologic diseases at Harvard Medical ...

More than half of 95 centenarians had a low amyloid load and 9% had no amyloid, autopsy data showed. A third of centenarians had a high amyloid load comparable to Alzheimer's disease. Five ...

While amyloid β plaques are hallmarks of Alzheimer’s disease (AD), recent research suggests that they aren’t the only players in the neurodegenerative disorder. Genome-wide association studies and RNA ...

Piller is an investigative journalist for Science. In November 2022, Dennis Selkoe, a Harvard professor of neurologic diseases and among the most celebrated and prolific Alzheimer’s researchers, ...

A recent study tests a new drug, gantenerumab on people with a genetically inherited form of Alzheimer’s disease. For people with this condition, dementia is almost inevitable. Gantenerumab helps ...

A research group has revealed that amyloid-beta detected in blood is secreted from peripheral tissues (pancreas, adipose tissue, skeletal muscle, liver, etc.) that are sensitive to glucose and insulin ...