For patients with brain metastases, treatment with an antibody-drug conjugate (ADC) at the same time as stereotactic radiotherapy significantly raises the risk of symptomatic radiation necrosis, a new ...

Immune checkpoint inhibitors and stereotactic radiosurgery do not increase the risk of necrosis among patients with NSCLC who have brain metastases, according to research. Treatment with immunotherapy ...

While targeted radiation can be an effective treatment for brain tumors, subsequent potential necrosis of the treated areas can be hard to distinguish from the tumors on a standard MRI. A new study ...

Radiation-induced brain injury (RIBI) is a serious and often delayed complication of cranial radiotherapy, which remains a cornerstone in the treatment of brain tumors such as gliomas, metastases, and ...

TORONTO, Dec. 8 2025 — While targeted radiation can be an effective treatment for brain tumours, subsequent potential necrosis of the treated areas can be hard to distinguish from the tumours on a ...

Radiotherapy induces DNA damage and oxidative stress, leading to endothelial injury and blood-brain barrier disruption, which triggers neuroinflammation, microvascular dysfunction, and neuronal ...