Researchers reveal the intricate molecular landscape of triple-negative breast cancer (TNBC), uncovering actionable spatial archetypes and gene signatures that pave the way for personalized therapies ...

BRCA1/2 and Other Predisposition Genes in High-Risk Hormone Receptor+/Human Epidermal Growth Factor Receptor 2– Breast Cancer Treated With Endocrine Therapy With or Without Palbociclib: A Secondary ...

Researchers at the Icahn School of Medicine at Mount Sinai in New York, Boston Medical Center, and Boston University School of Medicine have developed software to help scientists more easily analyze ...

Advancements in spatial proteomic workflows, featuring enzyme-activated spatial amplification reagents, have revolutionized cancer research capabilities. This webinar will include an explanation of ...

Spatial transcriptomic analysis of the ImmunoADAPT trial: Neoadjuvant endocrine therapy combined with palbociclib and avelumab in early-stage ER-positive breast cancer. This is an ASCO Meeting ...

This figure shows how the STAIG framework can successfully identify spatial domains by integrating image processing and contrastive learning to analyze spatial transcriptomics data effectively.

SAMBAI, a team funded through the Cancer Grand Challenges initiative, reported that Akoya Biosciences’ PhenoCycler ®-Fusion system will be the foundational spatial proteomics technology used to ...

The central promise of precision medicine is to provide right-sized and personalized care, patient by patient, instead of hewing to a singular clinical pathway for all patients who have a particular ...

Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs, MDSCs, and Tregs-orchestrate a tumor-permissive microenvironment.