Conservation of genomic sequences between species indicates regions of functional importance, containing protein-coding gene, non-coding genes or regulatory elements. In the December 5 Nature, ...

The unveiling of the DNA sequences of human chromosomes represents a new chapter in the unfolding story of genomics, but one with roots in the half-century-old field of cytogenetics. Chromosome-level ...

How does the CRISPR Down Syndrome breakthrough work to remove the extra chromosome 21? We are closer than ever to a world where a genetic condition affecting one in every 700 babies could be addressed ...

Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in the United States with DS-approximately 2,600-also have congenital heart defects (CHDs). What is ...

People with a third copy of chromosome 21, known as trisomy 21, are at high risk of developing acute myeloid leukemia (AML), an aggressive form of blood cancer. Scientists have now identified the ...

Scientists in Japan have used gene-editing technology to remove the extra chromosome responsible for Down syndrome, at least in lab-grown human cells. The project, led by Dr. Ryotaro Hashizume of Mie ...

Scientists have transplanted a nearly entire human chromosome in mice in a medical and technical breakthrough that could reveal new insights into Down syndrome and other disorders. The genetically ...

People with a third copy of chromosome 21, known as trisomy 21, are at high risk of developing Acute Myeloid Leukaemia (AML), an aggressive form of blood cancer. Scientists led by the Department of ...