The steepness hypothesis has been evolving over many years but it remains speculative, unclear and incomplete. We make five propositions. First, the decision to divide or not divide, to live or die, ...

This is a preview. Log in through your library . Abstract Achieving proper polarity is essential for cellular function. In bacteria, cell polarity has been observed by using both morphological and ...

Planar cell polarity (PCP) is a polarity axis that organizes cells in the plane of the tissue. PCP is conserved in metazoans and is essential for proper development and tissue homeostasis. Asymmetric ...

TORONTO – The question of how neurons and their axons establish spatial polarity and direction in tissues and organs is a fundamental question of any organism or biological system. Our cells and axons ...