The AI tool AlphaFold has been improved so that it can now predict the shape of very large and complex protein structures. Researchers have also succeeded in integrating experimental data into the ...
In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...
Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein design,” ...
Scientists from Scripps Research have uncovered new structures of transthyretin, a protein that moves important hormones like thyroxine through blood and spinal fluid. Misfolded versions of the ...
Proteins are the molecular machines of cells. They are produced in protein factories called ribosomes based on their blueprint—the genetic information. Here, the basic building blocks of proteins, ...
Giving Structure to Language: Profluent’s AI Models Move toward Precise and Steerable Protein Design
The “ChatGPT moment” for biology proceeds to unfold as protein language models, or machine learning tools trained on large databases of protein sequences, work to decode the language of life with the ...
Proteins are the building blocks of life. These biomolecules comprise chains of amino acids that fold into precise shapes to perform specific jobs in nature. But these elegant structures form only ...
Jane Richardson never considered herself an artist. Then, in the late 1970s, the structural biologist found herself in need of some colored pencils, pastels and sketching paper. Richardson, a ...
A three-decade-old competition that has spawned three Nobel laureates is becoming victim to the chaos at the National Institutes of Health. The Community Wide Experiment on the Critical Assessment of ...
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