Warshel's model shows that the engineered enzyme takes the shape of many keys, with all fitting electrostatically in the same lock. This should offer a new option for enzyme design.

Researchers devised a reversibly lockable DNA device for enclosing an enzyme and controlling its access to substrates named DNA Vault. Read more.

The researchers identified enzyme 4VPMT1, which catalyzes a precursor called 4VP into becoming 4VA. The researchers also identified several molecules involved in binding 4VP with other chemicals ...