Euan Ashley's lab explores the intricate interactions of gene variants. Tiny "typos," or genetic mutations, can sneak into segments of DNA. Many of these are harmless, but some can cause health ...

Alzheimer's disease (AD), a neurodegenerative disorder marked by amyloid plaque buildup and cognitive decline, remains a challenging condition to understand at the molecular level. While substantial ...

A new study has developed a powerful computational method that can detect how genes interact with each other to influence complex traits in humans at a scale previously impossible. The new method was ...

How do our genes determine our appearance and our susceptibility to disease? This question is central to biomedical research, and today we can sequence thousands of human genomes to identify these ...

Alopecia refers to hair loss and can affect the scalp, eyebrows, eyelashes, and other areas of the body. There are different types of alopecia including androgenetic alopecia, alopecia areata, anagen ...

Scientists have discovered an interaction between genes that increases the risk of developing a type of alopecia. Scientists have discovered an interaction between genes that increases the risk of ...

Despite rapid advances in reading the genetic code of living organisms, scientists still face a major challenge today—knowing a gene's sequence does not automatically reveal what it does. Even in ...

Our bodies follow a natural 24-hour cycle known as the circadian rhythm that influences everything from sleep to metabolism. While scientists have long known that certain core circadian clock genes ...