Researchers developed a fluorescence quenching assay to probe the integrity of the cell membrane coating of biomimetic nanoparticles (NPs) , discovering that the great majority of the cell membrane ...
Multiplex assay tech detects multi-biomolecules in single samples on xMAP/CBA, with high sensitivity and consistency ...
Modern bioassays tend to fall under three common modalities: colorimetric, luminometric or fluorometric. Colorimetric assays record the amount of light absorbed by a reporter compound. This absorbance ...
Fluorescent dyes are tools used throughout biotechnology and medicine that offer a unique method of detecting and quantifying the presence of a target molecule, cell, or tissue within an even more ...
The latest advances in genome sequencing indicate proteases occur naturally in all organisms and account for about 2% of the human genome and 1–5% of genomes of infectious organisms. The human genome ...
A direct rate assay for plasminogen activator has been developed using a synthetic fluorogenic peptide substrate, 7-(N-Cbz-glycylglycylargininamido)-4-methylcoumarin trifluoroacetate. The assay ...
In a recent study posted to the bioRxiv* pre-print server, a team of researchers used an assay toolset for discovering new transmembrane protease serine 2 (TMPRSS2) inhibiting drug repurposing ...
Sometimes, toxic side effects aren't discovered until fairly late in the drug development process, when substantial amounts of time and money have already been invested in clinical trials. Even though ...
Gprotein-coupled receptors (GPCRs) are an important class of receptor in modern drug discovery. This superfamily of receptors is highly tractable for drug discovery purposes because many of these ...
What’s the best method for assessing cell viability? Trypan blue is widely used in cell culture labs for selectively staining dead cells and tissues, but some sample types present challenges for ...
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