He is encouraged to exploit this good-luck charm reputation by his long-time best friend Dr. Stu Klaminsky, a sex-obsessed, sex-starved schlub who became a plastic surgeon so he could masturbate ...

Cursed since childhood, dentist Charlie Kagan (Dane Cook) cannot find the right woman. Even worse, he learns that each of his ex-girlfriends finds true love with the man she meets after her ...