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Interferon signal reprograms macrophage mitochondria to promote inflammation resolution, finds study
When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...
A new study shows type I interferon fine-tunes macrophage mitochondria through the protein ISG15, boosting dead-cell ...
Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.
Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal ...
Shi’s study, "Selective suppression of melanoma lacking IFN-γ pathway by JAK inhibition depends on T cells and host TNF signaling," was recently published in Nature Communications. “Concerted efforts ...
Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal ...
Interferon signatures may be a candidate biomarker for early identification of response to lupus nephritis induction treatment. Persistent type I interferon-driven transcriptional activity in ...
Why does the COVID-19 virus make some people sicker than others? For years, scientists have looked to a critical piece of immune system machinery - known as the interferon pathway - for answers. There ...
Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal ...
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