Brown adipose tissue (BAT) dissipates energy as heat. In doing so, brown fat serves as a biological heater in humans—keeping newborns warm, and in adults, brown fat activation positively correlates ...

Brain tissue can die as the result of stroke, traumatic brain injury, or neurodegenerative disease. When the affected area includes the motor cortex, impairment of the fine motor control of the hand ...

The drug inosine appears to be a safe and effective way to raise blood and cerebrospinal fluid urate levels in patients with early Parkinson disease (PD), suggesting it may be a potential strategy to ...

The most recent developments in the field of A-to-I RNA modification, with a special emphasis on the roles of A-to-I in the genesis and progression of cancer. Adenosine-to-inosine (A-to-I) RNA editing ...

Physical Exercise Improves Mobility in Parkinson’s Disease For patients with early Parkinson's disease (PD), inosine seems safe and effective for raising urate levels. (HealthDay News) – For patients ...

The paper S.C. Kim et al., “Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA,” PNAS, 115:13318–23, 2018. Proponents of the RNA world theory argue that ...

A study has identified a molecule -- the purine inosine -- that boosts fat burning in brown adipocytes. The mechanism was discovered in mice, but probably exists in humans as well: If a transporter ...

Our prehistoric Earth, bombarded with asteroids and lightening, rife with bubbling geothermal pools, may not seem hospitable today. But somewhere in the chemical chaos of our early planet, life did ...

A drug patterned after a naturally occurring biological chemical enables rats to regain movement in extremities paralyzed by a stroke, a U.S.–Canadian team reports. The compound, called inosine, ...