Severe COVID-19 reveals distinct immune patterns tied to metabolism, not just antiviral response

Patients with COVID-19 can show several different antiviral immune response patterns, which may influence how the disease ...
The American Journal of Managed Care

Pegylated Interferons Have Promise but Also Unmet Potential in MPNs

Despite potential benefits, the therapy remains in limited use for myeloproliferative neoplasms (MPNs). Pegylated interferons are a meaningful therapeutic option for the treatment of ...
News Medical

Antiviral functions of interferon regulatory factors during human coronavirus infection

In a recent study posted to the bioRxiv* preprint server, researchers assessed the roles of the interferon (IFN) regulatory factors (IRFs): IRF1, IRF3, and IRF7 in infections by human coronaviruses ...
Medical Xpress

Team explores role of 'stimulator of interferon genes' in body's innate immune system

When pathogens attack the body, the innate immune system goes to work protecting against the invading disease. The innate immune system is the first line of defense. It detects precisely what the ...
Healio

Enpatoran bests placebo in improving lupus skin manifestations

Three dosing levels of enpatoran each reduced disease activity among patients with skin manifestations of cutaneous or ...