Cellarity, a clinical-stage biotechnology company developing Cell State-Correcting therapies through integrated multi-omics and AI modeling, today announced the publication of a seminal manuscript in ...

Massachusetts Institute of Technology (MIT), engineers developed a new liver tissue model to help reveal the stages of liver regeneration in hopes to help those individuals with liver disease, ...

Steatotic donor livers are highly susceptible to post-transplant dysfunction; however, the underlying mechanisms remain ...

Liver disease is a major global health problem, causing over two million deaths worldwide each year. While animal models have helped to understand liver biology, they often fail to accurately ...

The liver is the only internal organ that can regenerate itself. Remarkably, even if 70 percent of the liver is removed, its tissue can regrow into a full-sized organ within a matter of months. By ...

Yale researchers have created a functional “humanized” liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating ...

Using human induced pluripotent stem cells, researchers have built a miniature 3D liver model that replicates the critical interaction between hepatocytes and stellate cells. As chronic liver disease ...

Scientists have developed a functional human hepatic tissue in a mouse host. The human hepatic tissue, in the mice, is composed of human hepatocytes and non-parenchymal cells (NPCs) including human ...

Roughly 115 million adults worldwide are estimated to have metabolic dysfunction-associated steatohepatitis, or MASH, a ...

Human periportal assembloid, showcasing the three key cell types of the liver: portal fibroblasts (magenta), cholangiocytes (green), and hepatocyte nuclei (blue). All cell borders are delineated in ...