Plasma cell myeloma, characterized by clonally aberrant plasma cells that produce abnormal monoclonal Igs, is the most common indication for autologous hematopoietic progenitor cell transplantation ...

Clin Lymphoma Myeloma. 2010;10(4):278-280. Our study has several limitations. Clinical information on the patients studied was incomplete, in part because half of the serum specimens came from ...

We describe a family with five cases of multiple myeloma, three cases of monoclonal gammopathy of undetermined significance (MGUS), and five cases of prostate cancer in two generations. The putative ...

Reviewed by Catherine Lai, MD, MPH, Director of Leukemia, Assistant Professor, Georgetown University Medical Center, Lombardi Comprehensive Cancer Center Patients who receive a diagnosis of a ...

This transcript has been edited for clarity. Joseph Mikhael, MD: Hello. My name is Dr Joseph Mikhael, and welcome to Medscape InDiscussion: Multiple Myeloma. Today we're talking about screening for ...

Monoclonal gammopathy of undetermined significance (MGUS) is an abnormal finding of a blood test. It means there’s a specific protein present in your blood and is an early sign of certain types of a ...

The risk for patients with monoclonal gammopathy of undetermined significance developing multiple myeloma is double if they have a specific category of rheumatic diseases compared with those without ...

The rate of MGUS among hospitalized patients over 50 was twice as high as that of the same age group in the general population. Higher rates of MGUS were prevalent among patients who had elevated ...

Serum protein electrophoresis (SPEP) is a clinical tool used to screen for monoclonal gammopathy, thus it is a critical tool in the evaluation of patients with multiple myeloma. However, SPEP ...

Antigen-driven selection has been implicated in the pathogenesis of monoclonal gammopathies. Patients with Gaucher’s disease have an increased risk of monoclonal gammopathies. Here we show that the ...

Serum protein electrophoresis (SPEP) is a clinical tool used to screen for monoclonal gammopathy, thus it is a critical tool in the evaluation of patients with multiple myeloma. However, SPEP ...