Inductive Bio, an AI drug discovery partner developing virtual chemistry labs, received an up to $21M award to lead a project to develop next-generation models of drug toxicity to advance safer ...

Scientists at The Scripps Research Institute (TSRI) have found that deep brain stimulation (DBS) can greatly reduce the compulsion to use heroin in standard rat models of addiction. Rats that were ...

Many drugs still fail after promising preclinical results, raising difficult questions about how disease is modelled in the ...

Does using alcohol, nicotine, or cannabis engender addiction by changing the structure of brains, or does the structure of brains incline some people toward using those substances? In standard brain ...

For decades, the pharmaceutical industry has discussed moving away from in vivo models in preclinical research. Now, it’s more than a conversation. The FDA’s roadmap for reducing animal testing, ...

Isomorphic Labs is developing a new engine for AI drug discovery ...

Genetically-humanized FcRn mice provide translational pharmacokinetics (PK) and pharmacodynamics (PD) data for antibody-based therapeutics. The image illustrates a therapeutic antibody (blue) adhering ...

Despite decades of progress in pharmaceutical R&D, the earliest phase of drug discovery—where molecules are conceived and designed—remains costly, inefficient, and burdened by high failure rates. Most ...

The International Council on Harmonisation (ICH) announced the adoption of its M15 guideline, which aims to harmonize general principles and best practices for utilizing model-informed drug ...

Grace Point Treatment Center has released an educational article examining “how drug addiction is assessed and treated within licensed clinical environments”. The resource is positioned as an ...