Assessment of organ dysfunction lies at the heart of contemporary critical care, offering an objective framework to quantify the severity and progression of multi-organ impairment in the intensive ...

Adding an SGLT2 inhibitor to standard care did not improve clinical outcomes in critically ill patients with acute organ dysfunction, an open-label randomized trial involving intensive care units ...

The Journal of the American Medical Association (JAMA) has recently published the updated version of the Sequential Organ Failure Assessment (SOFA), the global reference system in intensive care ...

Doctors use the sequential organ failure assessment (SOFA) score, previously known as the sepsis-related organ failure assessment, to measure a person’s organ function or failure rate. SOFA is a ...

Even after three years since the emergence of COVID-19, much remains unknown about how it causes severe disease, including the widespread organ damage beyond just the lungs. Increasingly, scientists ...

The authors make the point that bowel functions in general are associated with a lot of health outcomes. Direct association would be somebody with severe constipation, or the long term can be and ...

Care of patients with systemic immunoglobulin light chain (AL) amyloidosis has undergone transformative changes, leading to marked, steady progress in outcomes for patients over the past four decades.

Lung transplantation has evolved over 60 years from an experimental to an accepted standard treatment for life-threatening lung disease. Suitable recipients can expect improved survival and quality of ...

Providers should evaluate all patients with new-onset hypertension for evidence of end organ damage, guidelines say, but researchers have found gaps in that process. Researchers at Indiana University ...

Severe COVID-19 arises in part from the SARS-CoV-2 virus's impact on mitochondria, tiny oxygen-burning power plants in cells, which can help trigger a cascade of organ- and immune system-damaging ...

Pelvic floor dysfunction can contribute to chronic urinary tract infections. Relaxing the pelvic floor muscles in physical ...