Cholesterol synthesis and gallstone formation are promoted by trimethylamine-N-oxide (TMAO), a derivative of trimethylamine, which is a metabolite of gut microbiota. However, the underlying mechanisms ...

The gallbladder is a small, grape sized, organ attached to the digestive tract. It secretes a fluid called bile into it in response to a meal. Bile emulsifies dietary fats by increasing their exposure ...

I have a patient with gallstones. His alkaline phosphatase is 1800 (probably due to stones in the common bile duct [CBD]) and bilirubin is normal. What would be the best approach for management of ...

Gut microbiota produce trimethylamine, which enters the liver via the portal circulation and is primarily oxidized by FMO3 to produce TMAO. TMAO upregulates hepatic PCSK9 gene expression while ...

Your gallbladder is a small organ below your liver that stores bile, a green-yellow liquid that helps your digestive system. When something is blocking the bile duct, such as a gallstone, pain can ...

Characteristics of survivors with peritoneal mesothelioma. This is an ASCO Meeting Abstract from the 2023 ASCO Annual Meeting I. This abstract does not include a full text component.

Biliary pancreatitis occurs when gallstones develop in your gallbladder and block the duct that leads through your pancreas to your small intestines. Gallstones develop from hardened pieces of ...

Bariatric surgery is widely acknowledged as an effective intervention for morbid obesity, offering significant and sustained weight loss. However, rapid weight reduction following these procedures is ...