Inherited platelet disorders represent a heterogeneous group of genetic conditions that affect the number, size, or function of platelets, with clinical manifestations ranging from mild mucocutaneous ...

Platelets are an important part of the atherothrombotic process. They are involved in the pathways leading to atherosclerosis formation and progression and are central to the development of thrombus ...

Thrombocytopenic disorders include numerous causes of decreased platelet production or increased platelet destruction. Having too few platelets can lead to internal or serious bleeding after surgery ...

A new miniature 3D model of human bone marrow has just been described. The model may help clinicians predict which patients will benefit from a new therapy for blood platelet disorders, such as ...

Scientists have developed miniaturized 3-dimensional bone marrow models that could help physicians to predict which patients would likely respond to therapies for blood platelet disorders.

Megakaryocytes, which are derived from hematopoietic stem cell precursors in bone marrow, form and release platelets; these circulate in the blood for 8 to 10 days before they are removed by hepatic ...

Over two dozen cases of the rare blood disorder thrombocytopenia have been reported in people who have received COVID vaccines in the U.S. However, a link between COVID vaccines and the disease that ...

Belgian drugmaker Argenx said Tuesday that its antibody medicine failed to achieve the goals of a late-stage study for a platelet-destroying autoimmune disorder — a setback in the company’s efforts to ...

Hemophilia, von Willebrand disease, anemia, leukemias, or a low platelet count can cause bruising. A person should contact a doctor if they are concerned about their bruising. Bruising is one of the ...

Abstract and Introduction Review of Normal Platelet Physiology and Megakaryocytopoisis Qualitative Platelet Abnormalities Conclusion References Nitric oxide (NO) is another drug used in the neonatal ...