A new study reveals a possible way to make CAR T-cell therapy more durable and effective by targeting a single ...
A protein doctors routinely use to measure how aggressively tumors are growing may also help prevent the chromosome errors ...
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The key to attacking 'undruggable' proteins: Transient clustering state reveals a moving target
Intrinsically disordered proteins lack a fixed structure, which is why they have been considered "undruggable" targets for drug development for years. However, these proteins play a key role in ...
A small molecule modulates the oligomerization and condensation of the protein (left, untreated). Upon addition of the molecule (right), these condensates become more rigid, effectively blocking the ...
Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have developed a new cytokine-armored CAR-T cell therapy ...
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Immune memory cells in ovarian cancer produce tumor-targeting antibodies, opening a vaccine path
While we tend to quickly forget having been ill or having received a vaccine, the immune system remembers remarkably well. It ...
A new study found that immune cells called neutrophils may contribute to schizophrenia by generating and activating the ...
Introducing a new RNA-seq platform for intracellular multimodal profiling that could transform cancer research and ...
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