RNA molecules play vital roles in the human body by transferring genetic information and regulating gene activity. Some RNA molecules act as enzymes, called ribozymes, that facilitate essential ...

Programmable ribozymes that can attach non-natural amino acids to specific tRNAs may expand the range of amino acids available for protein engineering. To manipulate protein biosynthesis requires a ...

In new research published in the journal Angewandte Chemie, scientists applied a high throughput methodology to study the ribozyme in an innovative way. While work in this area has typically used ...

RNA transcripts containing the hammerhead ribozyme have been engineered to self-destruct in the presence of specific nucleoside 3′,5′-cyclic monophosphate compounds. These RNA molecular switches were ...