In the Alzheimer’s disease brain, synaptic loss correlates with cognitive decline, and is considered a sign of disease progression. But is synaptic loss always bad? Provocative new data from several ...

Problems with the brain's ability to "prune" itself of unnecessary connections may underlie a wide range of mental health disorders that begin during adolescence, according to research published today ...

A new study by Weill Cornell Medicine and Cornell University has come up with more explanations of how gut microbes communicate with the brain neurons. The study, published in the journal Nature on ...

Researchers from Kyushu University discovered a previously unrecognized synaptic "hotspot" that forms during adolescence, challenging the long-held view that adolescent brain development was dominated ...

The brain is plastic throughout life, but never more so than from birth to young adulthood. It increases its volume by developing dendrites and axons that connect neurons in to each other, forming new ...

A research group led by Kazunobu Sawamoto, a professor at Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences and National Institute for Physiological Sciences, and ...

A multidisciplinary team of scientists has discovered the mechanism that controls synaptic pruning of new neurons in the adult brain. The team discovered that microglial cells control the number of ...

Welcome back to Birdbrained Science! Last time, we touched on the ‘bird’ aspect with migration and today, we’ll cover some brain stuff — let’s talk about pruning. However it happens, we know that once ...

An analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The ...