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Researchers uncover TRAT1's central role in T helper cell function

Researchers at the Medical University of Vienna have taken a closer look at a previously largely unknown component of the ...
The Scientist

Autoimmunity Plays a Role in ALS

Researchers identified immune cells that attacked the neuronal protein C9orf72 in individuals with ALS, spurring new ...
JSTOR Daily

Critical regulation of follicular helper T cell differentiation and function by Gα

Da-Sol Kuen, Miso Park, Heeju Ryu, Garam Choi, Young-Hye Moon, Jae-Ouk Kim, Keon Wook Kang, Sang Geon Kim, Yeonseok Chung Proceedings of the National Academy of Sciences of the United States of ...
Science Daily

Flu: Interferon-gamma from T follicular helper cells is required to create lung-resident memory B cells

During a bout of influenza, B cells interact with other immune cells and then take different paths to defend the body. One path is the B cells that differentiate into lung-resident memory B cells, or ...
ascopubs.org

A phase II study of an anti-telomerase CD4+ T-helper vaccine (UCPVax) with or without temozolomide in newly diagnosed glioblastoma.

Patritumab deruxtecan (HER3-DXd) in active brain metastases (BM) from metastatic breast (mBC) and non–small cell lung cancers (aNSCLC), and leptomeningeal disease (LMD) from advanced solid tumors: ...
ascopubs.org

Single cell sequencing reveals T follicular helper cells as the link between combination ICI therapy and the development of increased IRAEs.

Triple M overlap syndrome (TMOS): Evaluating immune checkpoint inhibitor-related overlap syndrome of myocarditis, myositis and myasthenia gravis using an international pharmacovigilance database.
Kaleido Scope

Flu: Interferon-gamma from T follicular helper cells is required to create lung-resident memory B cells

Unlike antibody-producing B cells that help fight the current infection, the long-lived, non-circulating lung-BRMs migrate to the lungs from draining lymph nodes. They reside there permanently and lie ...