Construction of a self-regenerating biochemical system is critical for building a synthetic cell. An essential step in building a self-regenerative system is producing a complete set of tRNAs for ...
Premature transcription termination yields a wealth of unadenylated (pA −) RNA. Although this can be targeted for degradation by the Nuclear EXosome Targeting (NEXT) complex, possible backup pathways ...
Scientists have discovered how two transcription factors form a reciprocal regulatory circuit that controls T-cell exhaustion and migration during viral infection, which may inform future therapeutic ...
Cell-free, in vitro protein expression is a welcome alternative to time-consuming cell-based systems and appeals to scientists interested in toxic, insoluble, or rapidly degraded proteins incompatible ...