New sequencing tools revealed inflammatory brain cell clusters, age-related genetic changes, and vulnerable regions involved ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the technology has both laid the foundation for building cell atlases and allowed ...

Researchers develop IRISeq and EnrichSci to map cellular neighborhoods and analyze rare aging cells in the brain simultaneously.

While bulk sequencing quickly became the preferred method, scRNA-seq has increased in popularity in the last decade. In 2015, just 6 % of RNA-seq papers used single-cell methodologies. By 2025, the ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...