Chilly fingers and toes are generally nothing to worry about, but they can sometimes indicate a more serious condition.

Certain chemotherapy drugs, notably capecitabine, can cause a side effect known as palmar-plantar erythrodysesthesia (hand-foot syndrome), a painful swelling and inflammation of the hands and feet ...

The study covered in this summary was published on Research Square as a preprint and has not yet been peer reviewed. PLD is a key drug for platinum-resistant recurrent ovarian cancer but the risk for ...

Fingers frozen to the bone? It’s normal to be colder in the winter — but what’s not normal is extremities growing so cold that they go numb and turn white. Fortunately, it could very well be a ...

Feeling cold in your hands and feet is common and usually not a concern, even though it may feel unbearable in the colder ...

European Union (EU) vs. non-EU (NOEU) countries study compliance: the experience of the phase III FLORENCE study testing febuxostat in the Tumor Lysis Syndrome (TLS) prevention. This is an ASCO ...

Hand-foot syndrome (HFS), or palmoplantar erythrodysesthesia, is a dermatological toxicity produced by the fluoropyrimidine chemotherapy agents capecitabine and fluorouracil and affects 43-71% of ...

Hand-foot syndrome (HFS) is a dose-limiting side effect of capecitabine. Celecoxib prevents HFS by inhibiting cyclooxygenase-2 (COX-2) that is upregulated because of the underlying associated ...

Polydactyly is the term for when someone has extra digits, or fingers or toes. It usually means that a baby is born with at least six fingers on one or both hands or six toes on one or both feet. It's ...