eLife4h
Unsupervised discovery of family specific vocal usage in the Mongolian gerbil
Gerbils exhibit stable, family-specific vocal dialects over weeks, suggesting vocal communication may play a key role in representing kinship in natural social groups.
eLife4h
Contributions of associative and non-associative learning to the dynamics of defensive ethograms
Associative and non-associative learning mechanisms summate to produce robust and complex conditioned behavior profiles, opening new avenues to in-depth investigations of defensive responses and ...
eLife5h
Cytoskeleton: Rearranging to resist cell death
Cytoskeleton rearrangements promote formation of a giant structure called a GUVac that stops cells from dying when they become detached from the extracellular matrix.
eLife3d
An evolutionarily conserved Hox-Gbx segmentation code in the rice coral Montipora capitata
The authors studied the development of mesentery borders in the rice coral Montipora, a new experimental system, to complement existing data from the sea anemone Nematostella. They make a solid case ...
eLife3d
Progressive neural engagement within the IFG-pMTG circuit as gesture and speech entropy and MI advances
In this study, employing information-theoretic metrics, we quantified gesture and speech information, alongside their interaction, utilizing entropy and mutual information (MI). Neural activities were ...
eLife3d
Imaging of brain electric field networks
We present a method for direct imaging of the electric field networks in the human brain from electroencephalography (EEG) data with much higher temporal and spatial resolution than functional MRI ...
eLife3d
UBR-1 deficiency leads to ivermectin resistance in C. elegans
This important study will allow for a better understanding of anthelmintic drug resistance in nematodes, a growing concern for public health. The authors provide a detailed analysis of the role of UBR ...
eLife3d
Genomic and structural insights into Jyvaskylavirus, the first giant virus isolated from Finland
Universidade Federal de Minas Gerais, Institute of Biological Sciences, Department of Microbiology, Belo Horizonte, Brazil ...
eLife3d
Prefrontal working memory signal primarily controls phase-coded information within extrastriate cortex
This study uses electrophysiological recordings, causal manipulations of activity, and modeling to investigate how the maintenance of a spatial location in working memory affects the representation of ...
eLife3d
Deep learning linking mechanistic models to single-cell transcriptomics data reveals transcriptional bursting in response to DNA damage
The input of the DeepTXsolver is the parameters of the mechanism model, and the output is the corresponding stationary distribution solution of the model. The input to the DeepTXinferrer is the ...
eLife3d
Structure of the human CTF18 clamp loader bound to PCNA
Briola and co-authors determined the structure of the human CTF18 clamp loader bound to PCNA to high resolution, analyzed the structure, and tested a new mechanism involving a human-specific Ctf18 ...
eLife3d
Genetic inactivation of zinc transporter SLC39A5 improves liver function and hyperglycemia in obesogenic settings
This fundamental study substantially advances our understanding of the role of zinc in metabolism, specifically a newly established clinical link between mutations in the zinc transporter SLC39A5, ...