In a new proteomics extravaganza, scientists have unearthed groups of proteins that appear to be at the heart of Alzheimer’s disease pathogenesis. As described in Cell on September 25, scientists led ...

Doctor of Philosophy (PhD) University of Pittsburgh, Graduate School of Public Health, Department of Infectious Diseases and Microbiology Graduate Certificate in Public Health Preparedness and ...

Synonyms: High-copy SOD1-G93A, B6SJL.SOD1-G93A, Tg(hSOD1-G93A)1GUR mice, Gurney mice ...

SORL1 knockout, knockin, and transgenic mice are now in the Research Models database. The database will be updated as more models become available.

Score another one for amyloid immunotherapy. The anti-pyroglutamated amyloid antibody donanemab has posted positive top-line results in the Phase 3 Trailblazer-Alz2 study, according to an Eli Lilly ...

Biogen’s hopes for a quick regulatory approval of its anti-Aβ antibody aducanumab may be dimming. An advisory panel convened by the U.S. Food and Drug Administration was unimpressed by the evidence ...

Research over the last decade has shown that aggregated Aβ seeds can be transferred between people during rare medical procedures, sparking amyloidosis in the recipient. Could this result in ...

How does gene expression in the brain change with age? The answer remains murky, because the field has lacked a systematic, brain-wide survey of alterations across the lifespan. Researchers led by ...

A top researcher’s fall from grace sends shock waves through the scientific community. Such is the case with neuropathologist Eliezer Masliah, who stands accused of image falsification spanning 26 ...

On October 22, Biogen stunned the Alzheimer’s field by announcing that aducanumab—presumed dead last March after failing a futility analysis—appears to have worked in one of its two Phase 3 trials, ...

For years, scientists have been working toward blood tests for Alzheimer’s disease that could be used routinely in clinical practice. Now, they are on the cusp. At this year’s ADPD conference, held ...

Clinical researcher in biotech (Ionis).