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Birth defects happen during fetal development, often in the first three months of pregnancy. They can be mild or severe, and they can affect appearance, organ function, or development. Causes include ...

In cardiomyopathy caused by mutations in LMNA, which encodes the nuclear protein lamin A/C, cardiomyocyte nuclei are fragile and prone to rupture. This study reveals that this rupture arises from ...

Figure 3: Analysis of gene expression in adult Six5-mutant mice. The cataracts in mutant mice did not progress to full opacity during the study period, consistent with the low-grade cataracts ...

What Are Cleft Lip and Cleft Palate? Cleft lip and cleft palate are facial and oral differences that occur very early in pregnancy, while the fetus is developing inside the uterus. When the tissues in ...

A 65-year-old woman with a history of systemic lupus erythematosus (SLE) treated with prednisone and hydroxychloroquine 300 mg/day for 40 years, stage 3 chronic kidney disease, and hypertension ...

Atrial septal defects (ASD) are associated with an increased incidence of atrial arrhythmias, but their electrophysiological consequences are poorly defined. We hypothesised that conduction and ...