For immune cells, the actin cytoskeleton is more than a structural scaffold. Immune cells can migrate to sites of infection ...
Every time a eukaryotic cell divides, it faces a monumental challenge: It must carefully duplicate and divide its genetic ...
Molecular testing helps distinguish kidney cancer subtypes, ensuring patients get accurate diagnoses and treatment plans, ...
New research shows that cancer cells don’t just grow; they adapt when stressed. When squeezed inside tissues, they transform ...
A new study reveals that small cell lung cancer (SCLC) likely begins in basal stem-like cells rather than in neuroendocrine ...
Researchers explore innovative macrocyclic peptides to target small cell lung cancer, revealing promising therapeutic ...
Elevated GLUT5 expression in cancer cells has been associated with increased tumour aggressiveness. However, the role of fructose in remodelling the tumour microenvironment, particularly in modulating ...
Hepatocellular carcinoma (HCC) is often associated with an inflammatory setting. A plethora of cytokines are secreted in this milieu, actively contributing to the progression of the disease; however, ...
Copyright: © 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies. This single-arm, single ...
aDepartment of Genitourinary Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA bDepartment of Translational Molecular Pathology, The University of Texas MD ...
Patients with unresected LA SCCHN (oropharynx [p16-negative only], hypopharynx, or larynx) were randomly assigned 1:1 to six cycles of oral xevinapant 200 mg/day or matched placebo (once daily on Days ...
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