San Francisco 49ers tight end George Kittle wrapped up the 2024 season with a team-leading 1,106 receiving yards and eight ...

Watch highlights of San Francisco 49ers 2025 Pro Bowlers TE George Kittle, LB Fred Warner, DL Nick Bosa and FB Kyle Juszczyk ...

This was immediately followed by a 5-1 stretch in which the Cardinals got to 6-4 and first place in the NFC West. At this ...

Before entering any 49ers vs. Cardinals picks, you'll want to see the NFL predictions from the model at SportsLine. The model, which simulates every NFL game 10,000 times, is up well over $7,000 ...

D.J. Reed's path to free agency started with the San Francisco 49ers, who drafted him in the fifth round of the 2018 NFL ...

The NFL has seen a youth movement at head coach in recent years, but the Raiders went against that trend with their newest ...

This NFC West showdown features a matchup between two disappointments. The San Francisco 49ers were expected to compete for a Super Bowl, yet they trot into the final week of the regular season with a ...

The 49ers are a solid 9-7 betting the Over, but the Cardinals are just 7-8-1. Monitor gametime conditions with our live NFL weather info and learn how weather impacts NFL betting. Not intended for ...

The Arizona Cardinals will host the San Francisco 49ers in a Week 18 battle between two NFC West foes who will wonder where this NFL season went wrong for them. San Francisco (6-10) comes into the ...

The final week of NFL regular season action is here. The San Francisco 49ers and Arizona Cardinals will face off in an NFC West showdown. The 49ers are 6-10, while the Cardinals are 7-9.

The San Francisco 49ers and Arizona Cardinals play on Sunday, Jan. 5 at the Cardinals' State Farm Stadium in a game on the NFL Week 18 schedule. Which team will win the NFL Week 18 game?

The Cardinals are favorites to defeat the 49ers, according to the BetMGM NFL odds. Not interested in this game? Check out expert picks and best bets for every NFL game this week. NFL STATS CENTRAL ...