In the second round of the 2025 NFL Draft, the New Orleans Saints selected Louisville quarterback Tyler Shough, making him the first quarterback ever selected by the franchise in that round. The soon-to-be 26-year-old rookie was the third quarterback taken overall and begins his NFL career tied with the seventh-best odds of winning NFL Offensive Rookie of the Year honors,

Cornerback Quincy Riley will wear jersey No. 29, last worn by standout cornerback Paulson Adebo. Riley wore No. 3 throughout his college career at Louisville, but that number belongs to quarterback Jake Haener. Adebo represented No. 29 pretty well at the cornerback position and Riley will hope to continue his success.