Thorax

Establishing the top 10 research priorities for lung volume reduction treatment for people with COPD

Lung volume reduction procedures are an established evidence-based aspect of chronic obstructive pulmonary disease (COPD) ...
Thorax

Periodic breathing at altitude is an adaptive response: lessons for similar conditions at sea level

Healthy adult lowlanders sojourning above altitudes of 3000 m naturally develop periodic breathing (PB) ~40% of total sleep ...
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BTS/NICE/SIGN joint guideline on asthma: diagnosis, monitoring and chronic asthma management (November 2024) - summary of recommendations

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...
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Time for course correction? Rethinking oral steroids duration in acute asthma

Acute asthma exacerbations remain a major driver of morbidity and hospitalisation, accounting for substantial healthcare utilisation worldwide. Systemic oral corticosteroids (OCS) are the first-line ...
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Nasal high flow oxygen therapy in patients with COPD reduces respiratory rate and tissue carbon dioxide while increasing tidal and end-expiratory lung volumes: a randomised ...

Correspondence to Amanda Corley, Critical Care Research Group, Level 5 CSB, The Prince Charles Hospital, Rode Rd, Chermside, Brisbane, QLD 4032, Australia; amanda.corley{at}health.qld.gov.au The ...
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Inhaled corticosteroids in COPD and the risk of serious pneumonia

Departments of Epidemiology and Biostatistics and of Medicine, Center for Clinical Epidemiology, Lady Davis Research Institute, Jewish General Hospital, McGill University, Montreal, Québec, Canada ...
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Social isolation and loneliness as risk factors for hospital admissions for respiratory disease among older adults

Rising hospital admissions due to respiratory disease (RD) are a major challenge to hospitals. This study explored modifiable social risk factors among 4478 older adults from the English Longitudinal ...
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The COPD assessment test (CAT): response to pulmonary rehabilitation. A multicentre, prospective study

2 Guy's and St Thomas' Foundation NHS Trust, London, UK 3 Greenwich Primary Care Trust, London, UK 4 Croydon Primary Care Trust, London, UK Background The COPD (chronic obstructive pulmonary disease) ...
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Pulmonary fibrosis 4 months after COVID-19 is associated with severity of illness and blood leucocyte telomere length

Correspondence to Dr Christine Kim Garcia, Pulmonary and Critical Care Medicine, Columbia University Irving Medical Center, New York, NY 10032-3784, USA; ckg2116{at}cumc.columbia.edu The risk factors ...
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Radiomics analysis to predict pulmonary nodule malignancy using machine learning approaches

Background Low-dose CT screening can reduce lung cancer-related mortality. However, most screen-detected pulmonary abnormalities do not develop into cancer and it often remains challenging to identify ...
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Tuberculosis bacillary load, an early marker of disease severity: the utility of tuberculosis Molecular Bacterial Load Assay

In this comparative biomarker study, we analysed 1768 serial sputum samples from 178 patients at 4 sites in Southeast Africa. We show that tuberculosis Molecular Bacterial Load Assay (TB-MBLA) reduces ...
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Non-invasive ventilation in acute respiratory failure

S Baudouin, S Blumenthal, B Cooper, C Davidson, A Davison, M Elliot, W Kinnear (Chairman), R Paton, E Sawicka, L Turner (Secretary) Non-invasive ventilation (NIV) refers to the provision of ...