For patients with metastatic castration-sensitive prostate cancer (mCSPC) with homologous recombination repair (HRR) gene ...

An international study has shown how and when entirely new gene mutations, known as de novo mutations, originate in dogs. A ...

Scientists in Helsinki studied nearly 400 dog families to see how new DNA mutations arise in puppies. They found that older ...

For patients with HRRm prostate cancer receiving Akeega and Zytiga with prednisone, quality of life remained at baseline.

A targeted drug combination delays advanced prostate cancer in men with specific DNA repair gene mutations. A large international study led by researchers at UCL has found that a new combination of dr ...

Naked mole-rats seem to have found nature’s cheat code for longevity. Scientists discovered that small tweaks in one of their ...

“You can see that there was an initial reduction in the HR-QOL score in the niraparib arm, which may have been explained by the onset of the most frequently observed adverse events, which included ...

Rathkopf presented the Late-breaking abstract 91 - Patient-reported outcomes (PROs) from AMPLITUDE, a randomized placebo-controlled phase 3 trial of niraparib (NIRA) and abiraterone acetate (AA) plus ...

Mexican scientists call for regulations to distinguish between gene-edited and genetically modified (GM) crops.

Sex cells made from scratch could revolutionize human reproduction. But researchers are struggling to translate promising ...

More than two years after a positive top-line readout, AstraZeneca has to face the reality that a lack of an overall survival (OS) showing for its combo of Imfinzi and Lynparza could prohibit a ...

Combining the PARP1-selective inhibitor saruparib with an androgen receptor pathway inhibitor (ARPI) demonstrated promising efficacy and safety in patients with metastatic prostate cancer, according ...