The University of Oklahoma Sooners are set to take on Ole Miss Saturday at 11 a.m., but storms could impact the game.

A pair of Oklahoma offensive players, both of whom have started six games each, were downgraded to 'out' in Friday's SEC availability report

OU football will be without right tackle Derek Simmons for the Ole Miss game, per the latest availability report released Friday night.

The final Saturday of October brings a top-20 showdown in Norman as No. 13 Oklahoma (6–1, 2–1 SEC) hosts No. 8 Ole Miss (6–1, 3–1 SEC) in an 11:00 a.m. CT (ABC) tilt from Gaylord Family–Oklahoma Memorial Stadium.

Here are three defensive keys for the Sooners against the Rebels.

OU football players Jovantae Barnes, Logan Howland, Derek Simmons and Gentry Williams were all listed as questionable for Saturday's game vs. Ole Miss.

This article was originally published on www.si.com/college/oklahoma as Oklahoma has Opportunity Against an Ole Miss Defense That's Struggled This Season.

Find out why Will Hill is backing Ole Miss over the Sooners and why he believes the Giants are scary underdogs at the Eagles.