Protocol deviations don’t stay “minor” when they repeat or aren’t documented cleanly. In 2026, deviation management is inspection readiness: protect participant safety, preserve data integrity, and keep oversight defensible under FDA/EMA scrutiny.⁠ ⁠ This guide breaks down how to capture, categorize, analyze, and prevent deviations with GCP-aligned systems—so teams reduce rework and avoid findings.⁠ ⁠ This article breaks it down by:⁠ - What counts as a deviation and why “small” ones escalate⁠ -
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